HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyanogen Bromide → HCID 66940648, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyanogen Bromide | HCID 10476 | — |
| Reactant | methyl 2-amino-1H-benzo[d]imidazole-4-carboxylate | HCID 24730367 | — |
| Reactant | HCID 66940596 | HCID 66940596 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 66940648 | HCID 66940648 | — |
Reaction Steps
2.5 g (7.2 mmol) of 2,3-diamino-5-benzyloxy-benzoic acid benzyl ester was subjected to a similar cyclization condition as illustrated in intermediate A by using 2.3 g (21.6 mmol) of BrCN in methanol to produce 2-amino-6-benzyloxy-1H-benzoimidazole-4-carboxylic acid benzyl ester. LCMS: 375 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07893267B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-4a4d19d9d9c34ce2bde5c9ffb60448e9 |
| Source note | uspto-grants-2011_02 |