HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Dithionite → 2,3-Diamino-5-ethylsulfanyl-benzoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Dithionite | HCID 24489 | — |
| Reactant | 3-Amino-5-ethylsulfanyl-2-nitro-benzoic acid ethyl ester | HCID 66940810 | — |
| Solvent | Ethanol ethyl acetate water | HCID 86601158 | — |
| Product | 2,3-Diamino-5-ethylsulfanyl-benzoic acid ethyl ester | HCID 66940505 | — |
Reaction Steps
1.5 g (5.5 mmol) of 3-amino-5-ethylsulfanyl-2-nitro-benzoic acid ethyl ester was reduced by 2.9 g (16.6 mmol) of Na2S2O4 in 28 mL of ethanol/ethyl acetate/water (3:3:1) at 80° C. for 3 h to produce 2,3-diamino-5-ethylsulfanyl-benzoic acid ethyl ester. LCMS: 241 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07893267B2 |
| Source dataset | uspto-grants-2011_02 |
| ORD ID | ord-0ae70b47b9a043b2bc0014ad37b39f07 |
| Source note | uspto-grants-2011_02 |