Benzoxazole → 2-(Oxiran-2-ylmethoxy)benzothiazole

HRID 1368038Notes

Reaction equation

[OH:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[O:11]1[C:15]2[CH:16]=[CH:17]C=CC=2N=C1>>[O:11]1[CH2:15][CH:16]1[CH2:17][O:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1

Participants

Reactant 2

HCID 9228Benzoxazole

HCID 178517143HCID 178517143, compound

Product 1

HCID 125153732-(Oxiran-2-ylmethoxy)benzothiazole

Procedure

Compound 44 was prepared in the manner of compound 6 substituting 2-hydroxy-benzothiazole for compound 8 in partC-5 of Example 1.

Sources & evidence

ORD record: ord-a44f5d16d55e47a880f0b46228961571
Source dataset: uspto-grants-2003_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06573264B1

Reaction notes

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