Benzoxazole → 6-(Oxiran-2-ylmethoxy)benzothiazole

HRID 1368041Notes

Reaction equation

[S:1]1[C:5]2[CH:6]=[C:7]([OH:10])[CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.[O:11]1[C:15]2[CH:16]=[CH:17]C=CC=2N=C1>>[O:11]1[CH2:15][CH:16]1[CH2:17][O:10][C:7]1[CH:8]=[CH:9][C:4]2[N:3]=[CH:2][S:1][C:5]=2[CH:6]=1

Participants

Reactant 2

HCID 9228Benzoxazole

HCID 1518116-Hydroxybenzothiazole

Product 1

HCID 124221776-(Oxiran-2-ylmethoxy)benzothiazole

Procedure

Compound 48 was prepared in the manner of compound 6 substituting compound 16 for compound 8 in partC-5 of Example 1.

Sources & evidence

ORD record: ord-4d05e02c7c60403f878d4434545895aa
Source dataset: uspto-grants-2003_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06573264B1

Reaction notes

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