Benzoxazole → HCID 9813075, compound

HRID 1368054Notes

Reaction equation

[OH:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][N:6]=[CH:7]2.[O:12]1[C:16]2[CH:17]=[CH:18]C=CC=2N=C1>>[O:12]1[CH2:16][CH:17]1[CH2:18][O:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][N:6]=[CH:7]2

Participants

Reactant 2

HCID 9228Benzoxazole

HCID 30386Isoquinolin-5-ol

Product 1

HCID 9813075HCID 9813075, compound

Procedure

Compound 77 was prepared in the manner of compound 6 substituting 5-hydroxy-isoquinoline for compound 8 in part C-5 of Example 1.

Sources & evidence

ORD record: ord-afc6e96228854362973da0eaec301b41
Source dataset: uspto-grants-2003_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06573264B1

Reaction notes

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