Benzoxazole → 2-Methyl-7-(oxiran-2-ylmethoxy)quinoline

HRID 1368056Notes

Reaction equation

HRID 1368056 reaction equation
[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][C:8]([CH3:12])=[N:9]2)=[CH:4][CH:3]=1.[O:13]1[C:17]2[CH:18]=[CH:19]C=CC=2N=C1>>[CH3:12][C:8]1[CH:7]=[CH:6][C:5]2[C:10](=[CH:11][C:2]([O:1][CH2:19][CH:18]3[CH2:17][O:13]3)=[CH:3][CH:4]=2)[N:9]=1

Participants

3

Reactant 2

HCID 9228BenzoxazoleHCID 1354519692-Methylquinolin-7-ol

Product 1

HCID 225915922-Methyl-7-(oxiran-2-ylmethoxy)quinoline

Procedure

Compound 81 was prepared in the manner of compound 6 substituting 7-hydroxy-2-methyl-quinoline for compound 8 in part C-5 of Example 1.

Sources & evidence

ORD record
ord-1c184004cb4d4600abb7e921df0fb905
Source dataset
uspto-grants-2003_06
Patent number
US06573264B1

Reaction notes

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