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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 136810Generated: November 1, 2026

1,2-Dichloroethane → (RS)-1-{(4-chlorophenyl)[4-(pyrrolidylmethyl)phenyl]methyl}-3-[(3,5-difluorophenyl)(methylsulfonyl)methylene]azetidine

https://huagongshe.com/reaction/136810

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantPyrrolidineHCID 31268—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant(-)-1-[(4-Chlorophenyl)(4-formylphenyl)methyl]-3-[(3,5-difluorophenyl)(methylsulfonyl)methylene]azetidineHCID 22506638—
Product(RS)-1-{(4-chlorophenyl)[4-(pyrrolidylmethyl)phenyl]methyl}-3-[(3,5-difluorophenyl)(methylsulfonyl)methylene]azetidineHCID 10280566—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-b28c93303631459da7bc7ed73bae54fa
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)