Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | DL-alanine | HCID 602 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | N-Acetyl-L-alanine | HCID 88064 | — |
Reaction Steps
134 g (1.50 mol) of DL-alanine are introduced into acetic acid and treated dropwise with 230 g (2.25 mol) of acetic anhydride. The mixture is additionally stirred at 100° C. for 2 h to complete the reaction and the solvent is then stripped off in vacuo. The solid obtained is suspended in ethyl acetate and filtered off with suction. For purification, the solid is washed several times with diethyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06573263B2 |
|---|
| Source dataset | uspto-grants-2003_06 |
|---|
| ORD ID | ord-9a9234ea6c5b447986e1ff8d9e9064b5 |
|---|
| Source note | uspto-grants-2003_06 |
|---|
