Sodium Hydroxide → 2-(1-Hydroxyethyl)-5-phenylpentanoic acid

HRID 1368293Notes

Reaction equation

[OH:1][CH:2]([CH:4]([CH2:9][CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:5]([O:7]C)=[O:6])[CH3:3].[OH-].[Na+]>>[OH:1][CH:2]([CH:4]([CH2:9][CH2:10][CH2:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)[C:5]([OH:7])=[O:6])[CH3:3]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 18519827Methyl 2-(1-hydroxyethyl)-5-phenylpentanoate

Product 1

HCID 183340382-(1-Hydroxyethyl)-5-phenylpentanoic acid

Procedure

Analogously to Example 29A, 4.00 g (16.9 mmol) of methyl 2-(1-hydroxyethyl)-5-phenylpentanoate are reacted with 34.0 ml of a 1 M sodium hydroxide solution to give 2-(1-hydroxyethyl)-5-phenylpentanoic acid.

Sources & evidence

ORD record: ord-03d5dd6ddde843b5b50434e183c76d05
Source dataset: uspto-grants-2003_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06573263B2

Reaction notes

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