HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1368365Generated: October 30, 2026
Dihydrocoumarin → N-[3-(dimethylamino)propyl]-3-(2-hydroxyphenyl)propanamide
https://huagongshe.com/reaction/1368365
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dihydrocoumarin | HCID 660 | — |
| Reactant | N,N-Dimethyl-1,3-propanediamine | HCID 7993 | — |
| Product | N-[3-(dimethylamino)propyl]-3-(2-hydroxyphenyl)propanamide | HCID 15541838 | 106% |
Reaction Steps
N,N-Dimethyl-1,3-propanediamine (1.40 g) was added to 3,4-dihydrocoumarine (2.01 g) and stirred for 0.5 hour at 70° C., thereby yielding the entitled compound (3.60 g) as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06573297B2 |
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| Source dataset | uspto-grants-2003_06 |
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| ORD ID | ord-25d79b4121664640904b3e65132622d6 |
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| Source note | uspto-grants-2003_06 |
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