HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1368368Generated: October 26, 2026
Dihydrocoumarin → 3-(2-Hydroxyphenyl)-1-(4-methylpiperazino)-1-propanone
https://huagongshe.com/reaction/1368368
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dihydrocoumarin | HCID 660 | — |
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Product | 3-(2-Hydroxyphenyl)-1-(4-methylpiperazino)-1-propanone | HCID 18520257 | 103.4% |
Reaction Steps
N-Methylpiperazine (1.23 g) was added to 3,4-dihydrocoumarine (1.80 g) and stirred for 2 hours at 80° C., thereby yielding the entitled compound (3.12 g) as pale brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06573297B2 |
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| Source dataset | uspto-grants-2003_06 |
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| ORD ID | ord-65ccaf06b5544d2bb61181ef295f3ba7 |
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| Source note | uspto-grants-2003_06 |
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