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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1368371Generated: October 26, 2026

Dihydrocoumarin → 3-(2-hydroxyphenyl)-N-(3-morpholinopropyl)propanamide

https://huagongshe.com/reaction/1368371

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDihydrocoumarinHCID 660—
ReactantN-(3-Aminopropyl)morpholineHCID 61055—
Product3-(2-hydroxyphenyl)-N-(3-morpholinopropyl)propanamideHCID 18520254116.5%

Reaction Conditions

Temperature70 °C

Reaction Steps

N-(3-Aminopropyl)morpholine (1.77 g) was added to 3,4-dihydrocoumarine (1.81 g) and stirred for 1 hours at 70° C., thereby yielding the entitled compound (4.16 g) as pale yellow syrup.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06573297B2
Source datasetuspto-grants-2003_06
ORD IDord-93c2c716b2824eeda167cd6018d9196e
Source noteuspto-grants-2003_06