HCID 9852040, compound → HCID 18520265, compound

Participants

Reaction Steps

4N Hydrochloric acid/ethyl acetate solution (1.08 ml) was added to a solution containing 2-[3-(4-benzylpiperazino)-3-oxopropyl]phenyl N-octadecylcarbamate (2.21 g) in ethyl acetate (30 ml) at room temperature. After being stirred for 30 minutes, the reaction mixture was concentrated. The residue was recrystallized with the mixed solution of ethyl acetate-ethanol, thereby yielding the entitled compound (2.07 g) as white solid.

Provenance & Evidence