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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1368414Generated: November 1, 2026

Ethyl 1H-pyrrole-2-carboxylate → HCID 67281814, compound

https://huagongshe.com/reaction/1368414

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 1H-pyrrole-2-carboxylateHCID 255670—
Reactant5-Bromo-2-oxindoleHCID 611193—
ReactantHCID 85786882HCID 85786882—
ProductHCID 67281814HCID 6728181438%

Reaction Steps

5-Bromo-1,3-dihydroindol-2-one (212 mg, 1 mmol) was condensed with 5-formyl-1H-pyrrole-2-carboxylic acid (2-diethylaminoethyl)amide (prepared from ethyl pyrrole-2-carboxylate by method A, B and then C) to give 162 mg (38%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06573293B2
Source datasetuspto-grants-2003_06
ORD IDord-28311cd8d6374beb82c8326f8b3a88eb
Source noteuspto-grants-2003_06