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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1368421Generated: October 30, 2026

5-Methoxyoxindole → 5-(5-Methoxy-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-3-methyl-1H-pyrrole-2-carboxylic acid (3-diethylamino-propyl)amide

https://huagongshe.com/reaction/1368421

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-MethoxyoxindoleHCID 1514286—
Reactant5-formyl-3-methyl-1H-pyrrole-2-carboxylic acid (3-diethylaminopropyl) amideHCID 86586196—
Product5-(5-Methoxy-2-oxo-1,2-dihydroindol-3-ylidenemethyl)-3-methyl-1H-pyrrole-2-carboxylic acid (3-diethylamino-propyl)amideHCID 6728238939%

Reaction Steps

5-Methoxy-1,3-dihydroindol-2-one (82.5 mg, 0.5 mmol) was condensed with 5-formyl-3-methyl-1H-pyrrole-2-carboxylic acid (3-diethylaminopropyl)amide to give 80 mg (39%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06573293B2
Source datasetuspto-grants-2003_06
ORD IDord-77ef6daf63cf4d8a9c75c9e45e3d72ff
Source noteuspto-grants-2003_06