5-Bromo-2-oxindole → HCID 68758979, compound

HRID 1368429Notes

Reaction equation

HRID 1368429 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[CH2:5]2.[C:12]([C:20]1[C:21]([CH3:30])=[C:22]([C:27]([OH:29])=[O:28])[NH:23][C:24]=1[CH:25]=O)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[C:12]([C:20]1[C:21]([CH3:30])=[C:22]([C:27]([OH:29])=[O:28])[NH:23][C:24]=1[CH:25]=[C:5]1[C:4]2[C:8](=[CH:9][CH:10]=[C:2]([Br:1])[CH:3]=2)[NH:7][C:6]1=[O:11])(=[O:19])[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 6111935-Bromo-2-oxindoleHCID 21915652HCID 21915652, compound

Product 1

HCID 68758979HCID 68758979, compound

Procedure

5-Bromo-1,3-dihydro-indol-2-one was condensed with 4-benzoyl-5-formyl-3-methyl-1H-pyrrole-2-carboxylic acid using method D to give 4-benzoyl-5-(5-bromo-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-3-methyl-1H-pyrrole-2-carboxylic acid.

Sources & evidence

ORD record
ord-8d0c47912adb45b998f0e9b15aa58a8d
Source dataset
uspto-grants-2003_06
Patent number
US06573293B2

Reaction notes

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