6-(2-Methoxyphenyl)-1,3-dihydroindol-2-one → HCID 69106224, compound

HRID 1368451Notes

Reaction equation

HRID 1368451 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[CH:17]=[C:16]2[C:12]([CH2:13][C:14](=[O:18])[NH:15]2)=[CH:11][CH:10]=1.[CH3:19][N:20]([CH3:35])[CH2:21][CH2:22][NH:23][C:24]([C:26]1[C:30]([CH3:31])=[C:29]([CH:32]=O)[NH:28][C:27]=1[CH3:34])=[O:25]>>[CH3:19][N:20]([CH3:35])[CH2:21][CH2:22][NH:23][C:24]([C:26]1[C:30]([CH3:31])=[C:29]([CH:32]=[C:13]2[C:12]3[C:16](=[CH:17][C:9]([C:4]4[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=4[O:2][CH3:1])=[CH:10][CH:11]=3)[NH:15][C:14]2=[O:18])[NH:28][C:27]=1[CH3:34])=[O:25]

Participants

3

Reactant 2

HCID 105619756-(2-Methoxyphenyl)-1,3-dihydroindol-2-oneHCID 54380946HCID 54380946, compound

Product 1

HCID 69106224HCID 69106224, compoundYield 103.5%

Procedure

6-(2-Methoxyphenyl)-1,3-dihydroindol-2-one (30 mg, 0.13 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-dimethylaminoethyl)amide (30 mg) to give 0.06 g (100%) of the title compound as a yellow-orange gum.

Sources & evidence

ORD record
ord-ce304e90fb844e6fb8ea9c7229498037
Source dataset
uspto-grants-2003_06
Patent number
US06573293B2

Reaction notes

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