HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Phenyl-1,3-dihydro-indol-2-one → 2,4-Dimethyl-5-(2-oxo-6-phenyl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid (3-diethylaminopropyl)amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Phenyl-1,3-dihydro-indol-2-one | HCID 10536384 | — |
| Reactant | 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (3-diethylamino-propyl)-amide | HCID 20761799 | — |
| Product | 2,4-Dimethyl-5-(2-oxo-6-phenyl-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrole-3-carboxylic acid (3-diethylaminopropyl)amide | HCID 67280904 | 57% |
Reaction Steps
6-Phenyl-1,3-dihydroindol-2-one (1.5 g, 7.16 mmol) was condensed with 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (3-diethylaminopropyl)amide (2 g) to give 1.9 g (57%) of the title compound as an orange solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06573293B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-a3a4cdab926a45de92772a4594d082eb |
| Source note | uspto-grants-2003_06 |