2-Amino-5-(4-fluorophenyl)thiophene-3-carboxamide → tert-Butyl[(6-{[3-(aminocarbonyl)-5-(4-fluorophenyl)-2-thienyl]amino}pyridin-2-yl)methyl]methylcarbamate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH3:8])[CH2:9][c:10]1[n:11][c:12]([Br:16])[cH:13][cH:14][cH:15]1)=[O:17].[NH2:18][c:19]1[s:20][c:21](-[c:27]2[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]2)[cH:22][c:23]1[C:24](=[O:25])[NH2:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH3:8])[CH2:9][c:10]1[n:11][c:12]([NH:18][c:19]2[s:20][c:21](-[c:27]3[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]3)[cH:22][c:23]2[C:24](=[O:25])[NH2:26])[cH:13][cH:14][cH:15]1)=[O:17]Participants
3
Sources & evidence
- ORD record
- ord-3146a15aa1d54589a764b1372e6f69f3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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