Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Aminosalicylic Acid → 5-(4-Chlorobenzyl)aminosalicylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Aminosalicylic Acid | HCID 4075 | — |
| 반응물 | 1-Chloro-4-(chloromethyl)benzene | HCID 7723 | — |
| 생성물 | 5-(4-Chlorobenzyl)aminosalicylic acid | HCID 9814207 | 53% |
반응 단계
By following the similar procedure in Synthesis Example 1 by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and 4-chlorobenzyl chloride (630 mg, 3.91 mmole), 480 mg (53% yield) of 5-(4-chlorobenzyl)aminosalicylic acid was obtained as a white solid.: mp 227-228° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06573402B1 |
| 출처 데이터셋 | uspto-grants-2003_06 |
| ORD ID | ord-ebf4d36881d7424a9e8250717086d100 |
| 출처 메모 | uspto-grants-2003_06 |