HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon Dioxide → 4-Chloro-2-methylbenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon Dioxide | HCID 280 | — |
| Reactant | 2-Bromo-5-chlorotoluene | HCID 84476 | — |
| Reactant | CID 53628100 | HCID 178418400 | — |
| Product | 4-Chloro-2-methylbenzoic acid | HCID 348269 | — |
Reaction Steps
in stage a) 2-bromo-5-chlorotoluene is reacted with a secondary or tertiary organolithium compound, particularly preferably sec-butyllithium, and CO2 to give 4-chloro-2-methylbenzoic acid,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06573404B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-6ef3a90202264d5784d0fdb387121def |
| Source note | uspto-grants-2003_06 |