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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1368744Generated: November 1, 2026

Methyl iodide → 4-chloro-2-methyl-5-(methylsulfonyl)Benzoic acid

https://huagongshe.com/reaction/1368744

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium SulfiteHCID 24437—
ReactantChlorosulfonic acidHCID 24638—
Reactant4-Chloro-2-methylbenzoic acidHCID 348269—
Product4-chloro-2-methyl-5-(methylsulfonyl)Benzoic acidHCID 10824478—

Reaction Steps

in stage b) 4-chloro-2-methylbenzoic acid is reacted with chlorosulfonic acid, sodium sulfite and methyl iodide to give 2-methyl-4-chloro-5-methylsulfonylbenzoic acid,

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06573404B2
Source datasetuspto-grants-2003_06
ORD IDord-db2b22cf8b104bb58b0dcd60d09b15ea
Source noteuspto-grants-2003_06