HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → Methyl 3-chlorocarbonyl-2,4-dichlorobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Methyl 2,4-dichloro-3-hydroxycarbonylbenzoate | HCID 18517411 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Methyl 3-chlorocarbonyl-2,4-dichlorobenzoate | HCID 18517406 | 100% |
Reaction Steps
2 drops of dimethylformamide and 11.90 g (0.1 mol) of thionyl chloride were added to a solution of 5.00 g (0.02 mol) of methyl 2,4-dichloro-3-hydroxycarbonylbenzoate and 50 ml of dry toluene. The solution was heated under reflux for 4 hours. Removal of the solvent by distillation gave 5.35 g of methyl 3-chlorocarbonyl-2,4-dichlorobenzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06576596B1 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-5f793e16d369460e90d5794f30d8cbc0 |
| Source note | uspto-grants-2003_06 |