Isobutyric anhydride → HCID 86585445, compound

Participants

Reaction Steps

Compound 17 was prepared in the manner of compound 15 utilizing cyclopentanecarboxylic acid under conditions B for introduction of the ester group at the 5′ hydroxyl group, and isobutyric anhydride under conditions A for the introduction of the 2′ and 3′ hydroxyl groups: 1H NMR(CDCl3) δ1.05-1.23 (m, 12H), 1.52-2.05 (m, 8H), 2.26-2.38 (m,1H), 2.49-2.63(m,2H), 2.71-2.79 (m, 1H), 3.75-3.87(m,2H), 3.94-4.06(m,2H), 4.34-4.45 (m, 3H), 4.78-4.86(m, 1H), 5.58 (dd, 1H), 5.81 (dd, 1H), 6.17 (d, 1H), 6.95 (br s, 1H), 7.97 (s,1H), 8.37(s,1H).

Provenance & Evidence