化工社化工社 化学情報印刷レポート · 研究参考用
Methyl Isocyanate → N-[(5-{6[((3R)oxolan-3yl)amino]purin-9-yl}(3S,2R,4R,5R)3,4-dihydroxyoxolan-2-yl)methyl](cyclopentylamino)carboxamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl Isocyanate | HCID 12228 | — |
| 反応物 | Cyclopentyl Isocyanate | HCID 643500 | — |
| 反応物 | n-[(5-{6-[((3r)Oxolan-3-yl)amino]purin-9-yl}(3s,2r,4r,5r)-3,4-dihydroxyoxolan-2-yl)methyl](methylamino)carboxamide | HCID 20592071 | — |
| 生成物 | N-[(5-{6[((3R)oxolan-3yl)amino]purin-9-yl}(3S,2R,4R,5R)3,4-dihydroxyoxolan-2-yl)methyl](cyclopentylamino)carboxamide | HCID 20592068 | — |
反応手順
Compound 76 was prepared in the manner of compound 24 substituting cyclopentyl isocyanate for methyl isocyanate and refluxing for 16 h [MS 448.3 (M+1)].
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06576620B2 |
| 出典データセット | uspto-grants-2003_06 |
| ORD ID | ord-2c15847345524b30a9e7e2f6435309b7 |
| 出典メモ | uspto-grants-2003_06 |