HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Isocyanate → n-[(5-{6-[((3r)Oxolan-3-yl)amino]purin-9-yl}(3s,2r,4r,5r)-3,4-dihydroxyoxolan-2-yl)methyl](propylamino)carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Isocyanate | HCID 12228 | — |
| Reactant | Propyl isocyanate | HCID 61033 | — |
| Reactant | n-[(5-{6-[((3r)Oxolan-3-yl)amino]purin-9-yl}(3s,2r,4r,5r)-3,4-dihydroxyoxolan-2-yl)methyl](methylamino)carboxamide | HCID 20592071 | — |
| Product | n-[(5-{6-[((3r)Oxolan-3-yl)amino]purin-9-yl}(3s,2r,4r,5r)-3,4-dihydroxyoxolan-2-yl)methyl](propylamino)carboxamide | HCID 20592072 | — |
Reaction Steps
Compound 93 was prepared in the manner of compound 24 substituting propyl isocyanate for methyl isocyanate and refluxing for 16 h [MS 422.3 (M+1)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06576620B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-070a131323cf4905ad1a132946a23288 |
| Source note | uspto-grants-2003_06 |