332098-83-6 → HCID 9868280, compound

HRID 1368973Notes

Reaction equation

HRID 1368973 reaction equation
[Br:1][C:2]1[S:12][C:5]2[NH:6][C:7]([C:9]([OH:11])=O)=[CH:8][C:4]=2[CH:3]=1.Cl.[NH2:14][C@@H:15]([CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[C:16]([N:18]1[CH2:21][CH:20]([OH:22])[CH2:19]1)=[O:17]>>[CH2:23]([C@H:15]([NH:14][C:9]([C:7]1[NH:6][C:5]2[S:12][C:2]([Br:1])=[CH:3][C:4]=2[CH:8]=1)=[O:11])[C:16]([N:18]1[CH2:21][CH:20]([OH:22])[CH2:19]1)=[O:17])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 22556510332098-83-6HCID 69687670HCID 69687670, compound

Product 1

HCID 9868280HCID 9868280, compound

Procedure

2-Bromo-6H-thieno[2,3-b]pyrrole-5-carboxylic acid and (2S)-amino-1-(3-hydroxy-azetidin-1-yl)-3-phenyl-propan-1-one hydrochloride were coupled according to Procedure B.

Sources & evidence

ORD record
ord-29ade8672302428cba40acc11b6fb32b
Source dataset
uspto-grants-2003_06
Patent number
US06576653B2

Reaction notes

Loading…