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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1369042Generated: October 27, 2026

1-Ethynyl-4-fluorobenzene → Z-4-fluorostyryl 4-iodobenzylsulfide

https://huagongshe.com/reaction/1369042

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethynyl-4-fluorobenzeneHCID 522627—
ReactantSodiumHCID 5360545—
Reactant(4-Iodophenyl)methanethiolHCID 18518842—
ProductZ-4-fluorostyryl 4-iodobenzylsulfideHCID 86759007—

Reaction Steps

A solution of 4-fluorophenylacetylene (0.02 mol) and 4-iodobenzyl mercaptan (0.02 mol) and metallic sodium (0.02 g atom) is subjected to the General Procedure to form Z-4-fluorostyryl 4-iodobenzylsulfide. The title compound is obtained following oxidation.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06576675B1
Source datasetuspto-grants-2003_06
ORD IDord-8402cd548b99490a9bd6954bc701331e
Source noteuspto-grants-2003_06