2-Benzylcyclohexan-1-one → HCID 18517932, compound

HRID 1369054Notes

Reaction equation

HRID 1369054 reaction equation
[CH2:1](C1CCCCC1=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:15][CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH:17]1[CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH2:1]([NH:15][CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH:17]1[CH2:22][C:23]1[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 989452-Benzylcyclohexan-1-oneHCID 30183432-Benzylcyclohexan-1-amine

Product 1

HCID 18517932HCID 18517932, compound

Procedure

In a series of procedures similar to preparations A and B, 2-benzyl cyclohexanone was converted into 1-amino-2-benzylcyclohexane in 65% via the intermediate oxime. This material (3.05 g, 16.1 mmol) was then converted to the title compounds in a procedure similar to preparation C, isolated as an oil:

Workup

  1. customisolated as an oil

Sources & evidence

ORD record
ord-df982f9494fb474e81d68e4c24c500bd
Source dataset
uspto-grants-2003_06
Patent number
US06576632B1

Reaction notes

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