HCID 12071522, compound → HCID 12071524, compound

Participants

Reaction Steps

Under nitrogen stream, to a solution of 4-chloro-6-(4-hydroxy-1-butynyl)-1-(2-diethylaminoethyl)-3-hydroxy-3-(2-naphthyl)oxindole (8.6 mg, 0.0180 mmol) in methanol (1.5 mL) was added 10% palladium/carbon (4.0 mg). The mixture was stirred under hydrogen atmosphere at room temperature for one hour. After filtration with Celite, the solvent was removed to give the title compound (8.7 mg).

Provenance & Evidence