Acetone → 1-(p-Nitrobenzyloxycarbonyl)-4-iodopiperidine

HRID 136918Notes

Reaction equation

HRID 136918 reaction equation
[CH3:33][C:34](=[O:35])[CH3:36].[I-:32].[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7]([CH2:8][O:9][C:10](=[O:11])[N:12]2[CH2:13][CH2:14][CH:15]([O:18][S:19]([c:20]3[cH:21][cH:22][c:23]([CH3:24])[cH:25][cH:26]3)(=[O:27])=[O:28])[CH2:16][CH2:17]2)[cH:29][cH:30]1.[Na+:31]>>[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7]([CH2:8][O:9][C:10](=[O:11])[N:12]2[CH2:13][CH2:14][CH:15]([I:32])[CH2:16][CH2:17]2)[cH:29][cH:30]1

Participants

5

Reactant 4

HCID 180AcetoneHCID 923Sodium ionHCID 30165Iodide IonHCID 132927101-(p-Nitrobenzyloxycarbonyl)-4-(p-toluenesulfonyloxy)piperidine

Product 1

HCID 132927111-(p-Nitrobenzyloxycarbonyl)-4-iodopiperidine

Sources & evidence

ORD record
ord-569cf019d2a64295ac407950062f2d47
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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