HCID 22799775, compound → HCID 178478750, compound

HRID 1369181Notes

Reaction equation

HRID 1369181 reaction equation
C([C@@:8]([C:15]([OH:17])=[O:16])([CH2:10][CH2:11][CH2:12][CH2:13][NH2:14])[NH2:9])(OC(C)(C)C)=O.[Cl:18][O:19][N:20]=[CH:21][C:22]([F:25])([F:24])[F:23]>>[ClH:18].[ClH:18].[OH:19][N:20]=[C:21]([NH:14][CH2:13][CH2:12][CH2:11][CH2:10][C@@H:8]([C:15]([OH:17])=[O:16])[NH2:9])[C:22]([F:25])([F:24])[F:23]

Participants

3

Reactant 2

HCID 22799775HCID 22799775, compoundHCID 131722465HCID 131722465, compound

Product 1

HCID 178478750HCID 178478750, compound

Procedure

α-Boc-L-lysine is reacted with chlorotrifluoroacetaldoxime (J. Org. Chem. 49, (1984) 919-922) as described in Example 1 to afford the title compound.

Sources & evidence

ORD record
ord-69115017caf142e3a07e58c8ddc77af1
Source dataset
uspto-grants-2003_06
Patent number
US06576780B1

Reaction notes

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