HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 4-Formylphenylboronic acid pinacol ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Pinacol | HCID 6425 | — |
| Reactant | 4-Formylphenylboronic Acid | HCID 591073 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-Formylphenylboronic acid pinacol ester | HCID 2769536 | 93.1% |
Reaction Steps
A suspension of 5 g (33.3 mmol) of 4-formylphenylboronic acid and 3.93 g (33.3 mmol) of pinacol in 25 ml of toluene was refluxed on a water separator. When all the water of reaction had been removed, a clarifying filtration was carried out, and the solvent was removed by distillation until the product started to crystallize, giving 7.2 g (31 mmol) of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06576789B1 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-420657fc949e4342a9fd07868d106961 |
| Source note | uspto-grants-2003_06 |