HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Formylphenylboronic Acid → 4-(Hydroxymethyl)benzeneboronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Formylphenylboronic Acid | HCID 591073 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-(Hydroxymethyl)benzeneboronic acid | HCID 2734706 | 97% |
Reaction Steps
15 g (100 mmol) of 4-formylphenylboronic acid were dissolved in 200 ml of tetrahydrofuran, and 0.25 g of Raney nickel were added. A stream of hydrogen was passed through the reaction mixture for 8 hours, giving 14.8 g (97 mmol) of 4-(hydroxymethyl)phenylboronic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06576789B1 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-915e88b0609048e8910484e5665ba7ab |
| Source note | uspto-grants-2003_06 |