HCID 86590330, compound → 4-(Hydroxymethyl)benzeneboronic acid

HRID 1369188Notes

Reaction equation

HRID 1369188 reaction equation
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([B:9]([O-:17])[O:10]C(C(C)(C)C)C)=[CH:5][CH:4]=1)=[O:2]>CO>[OH:2][CH2:1][C:3]1[CH:4]=[CH:5][C:6]([B:9]([OH:17])[OH:10])=[CH:7][CH:8]=1

Participants

3

Reactant 1

HCID 86590330HCID 86590330, compound

Product 1

HCID 27347064-(Hydroxymethyl)benzeneboronic acidYield 96.2%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Analogously to Example 12, 12 g (52 mmol) of pinacolyl 4-formylphenylboronate were hydrogenated in 100 ml of methanol, giving 11.7 g (50 mmol) of 4-(hydroxymethyl)phenylboronic acid.

Sources & evidence

ORD record
ord-ae51afee5dca467ba248b0f2192d1283
Source dataset
uspto-grants-2003_06
Patent number
US06576789B1

Reaction notes

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