Butanedione → HCID 178465752, compound

Participants

Reaction Steps

A mixture of 0.1 mol of cis-decalin, 0.5 mol of biacetyl, 10 mmol of N-hydroxyphthalimide, 1 mmol of acetylacetonatocobalt(II), and 100 ml of acetic acid was stirred at 75° C. in an oxygen atmosphere at atmospheric pressure for 4 hours. The reaction mixture was concentrated to about 20% by weight and was then extracted with ethyl acetate, and the extract was concentrated and was then washed with hexane to yield 4a-acetyl-8a-hydroxy-cis-decalin (yield: 30%). The conversion rate from cis-decalin was 68%.

Provenance & Evidence