HCID 18518363, compound → HCID 18518314, compound

HRID 1369211Notes

Reaction equation

HRID 1369211 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:8]2(O)[C:16]3[C:11](=[CH:12][CH:13]=[C:14]([O:17][CH3:18])[CH:15]=3)[CH2:10][CH2:9]2)[CH:5]=[CH:6][CH:7]=1.COC1C=C2C(CCC2(C2C=CC=CC=2)O)=CC=1>>[F:1][C:2]1[CH:3]=[C:4]([CH:8]2[C:16]3[C:11](=[CH:12][CH:13]=[C:14]([O:17][CH3:18])[CH:15]=3)[CH:10]=[CH:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 18518363HCID 18518363, compoundHCID 18518366HCID 18518366, compound

Product 1

HCID 18518314HCID 18518314, compound

Procedure

According to the procedure of Preparation 10(a), except substituting 1-(3-fluorophenyl)-6-methoxy-1-indanol for the 6-methoxy-1-phenyl-1-indanol, the title compound was obtained as a colorless oil following silica gel chromatography (4% EtOAc/hexanes): MS (ES) m/e 241.1 (M+H)+.

Sources & evidence

ORD record
ord-7d3c6e283d9045afa9941e01c14f1890
Source dataset
uspto-grants-2003_06
Patent number
US06576643B2

Reaction notes

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