HCID 12743495, compound → HCID 18518371, compound

HRID 1369213Notes

Reaction equation

HRID 1369213 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][CH:20]=1)[CH2:5][C:6]1[CH:11]=[C:10]([O:12][CH3:13])[CH:9]=[CH:8][C:7]=1[CH2:14][C:15]([OH:17])=O.C(C1C=C(OC)C=CC=1CC(O)=O)C1C=CC=CC=1>>[F:1][C:2]1[CH:20]=[CH:19][C:18]2[C:15](=[O:17])[CH2:14][C:7]3[CH:8]=[CH:9][C:10]([O:12][CH3:13])=[CH:11][C:6]=3[CH2:5][C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 12743495HCID 12743495, compoundHCID 54188309HCID 54188309, compound

Product 1

HCID 18518371HCID 18518371, compound

Procedure

According to the procedure of Preparation 10(d), except substituting 2-(3-fluorobenzyl)-4-methoxyphenylacetic acid for the 2-benzyl-4-methoxyphenylacetic acid, the title compound was obtained as a white solid: Mp 129-130° C.; MS (ES) m/e 279.2 (M+Na)+.

Sources & evidence

ORD record
ord-a9aa3078d5774d7187b4a2f1491a25d8
Source dataset
uspto-grants-2003_06
Patent number
US06576643B2

Reaction notes

Loading…