HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl (+/-)-10,11-dihydro-10-hydroxy-3-methoxy-5H-dibenzo[a,d]cycloheptene-10-acetate → Ethyl (+/-)-10,11-dihydro-7-fluoro-3-methoxy-5H-dibenzo[a,d]cycloheptene-10-acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl (+/-)-10,11-dihydro-10-hydroxy-3-methoxy-5H-dibenzo[a,d]cycloheptene-10-acetate | HCID 18340682 | — |
| Reactant | ethyl (+/-)-10,11-dihydro-7-fluoro-10-hydroxy-3-methoxy-5H-dibenzo[a,d]cycloheptene-10-acetate | HCID 54499599 | — |
| Product | Ethyl (+/-)-10,11-dihydro-7-fluoro-3-methoxy-5H-dibenzo[a,d]cycloheptene-10-acetate | HCID 54358299 | — |
Reaction Steps
According to the procedure of Preparation 10(f), except substituting ethyl (±)-10,11-dihydro-7-fluoro-10-hydroxy-3-methoxy-5H-dibenzo[a,d]cycloheptene-10-acetate for the ethyl (±)-10,11-dihydro-10-hydroxy-3-methoxy-5H-dibenzo[a,d]cycloheptene-10-acetate, the title compound was obtained as a colorless oil following silica gel, chromatography (10% EtOAc/hexanes): MS (ES) m/e 329.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06576643B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-99f53055e40246a18ce398532fdc7232 |
| Source note | uspto-grants-2003_06 |