Sodium Hydroxide → HCID 11760895, compound

Participants

Reaction Steps

A solution of ethyl (±)-10,11-dihydro-3-[2-(6-aminopyridin-2-yl)-1-ethoxy]-5H-dibenzo[a,d]cycloheptene-10-acetate (0.030 g, 0.072 mmole) and 1.0 N NaOH (0.14 mL, 0.14 mmole) in MeOH (2 mL) was stirred at RT overnight, then was concentrated. The residue was dissolved in H2O and the pH of the solution was adjusted to 7 with 1.0 N HCl. Concentration and chromatography on a C-18 Bond Elute column (10:9:1 CH3CN/H2O/TFA) gave the title compound (0.013 g): MS (ES) m/e 389 (M+H)+.

Provenance & Evidence