HCID 12071478, compound → HCID 54189932, compound

HRID 1369258Notes

Reaction equation

HRID 1369258 reaction equation
[CH3:1][C:2]1[C:7]2[CH2:8][C:9]3[CH:22]=[C:21]([O:23][CH2:24][CH2:25][CH2:26][NH:27][C:28]4[CH:33]=[CH:32][CH:31]=[CH:30][N:29]=4)[CH:20]=[CH:19][C:10]=3[CH2:11][CH:12]([CH2:13][C:14]([O:16]CC)=[O:15])[C:6]=2[CH:5]=[CH:4][CH:3]=1.N1C=CC=CC=1NCCCOC1C=CC2C[C@H](CC(OCC)=O)C3C=CC=CC=3CC=2C=1>>[CH3:1][C:2]1[C:7]2[CH2:8][C:9]3[CH:22]=[C:21]([O:23][CH2:24][CH2:25][CH2:26][NH:27][C:28]4[CH:33]=[CH:32][CH:31]=[CH:30][N:29]=4)[CH:20]=[CH:19][C:10]=3[CH2:11][CH:12]([CH2:13][C:14]([OH:16])=[O:15])[C:6]=2[CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 12071478HCID 12071478, compoundHCID 54085680HCID 54085680, compound

Product 1

HCID 54189932HCID 54189932, compound

Procedure

According to the procedure of Example 6 (c), except substituting ethyl (±)-10,11-dihydro-6-methyl-3-[3-(pyridin-2-ylamino)-1-propyloxy]-5H-dibenzo[a,d]cycloheptene-10-acetate for the ethyl (R)-10,11-dihydro-3-[3-(pyridin-2-ylamino)-1-propyloxy]-5H-dibenzo[a,d]cycloheptene-10-acetate, the title compound was obtained as a white solid: MS (ES) m/e 417.3 (M+H)+. Anal. Calcd for C26H28N2O3.1.25 H2O: C, 71.13; H, 7.02; N, 6.38. Found: C, 71.33; H, 6.67; N, 6.01.

Sources & evidence

ORD record
ord-a9219ca3ecef474d804bb9a860d3b720
Source dataset
uspto-grants-2003_06
Patent number
US06576643B2

Reaction notes

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