HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 18519030, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 3-Bromo-1-propanol | HCID 12308 | — |
| Reactant | Phenol, o-mercapto-(6CI,7CI,8CI) | HCID 70718 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 18519030 | HCID 18519030 | — |
Reaction Steps
2-Hydroxythiophenol (1.00 g, 8.70 mmol) was added to a mixture of DMF (10 mL) and Cs2CO3 (2.90 g, 8.90 mmol). To this was added 3-bromopropanol (0.80 mL, 9.16 mmol) and the mixture was stirred for 20 min. The mixture was added to into water and extracted with EtoAc. The combined extracts were washed with water, dried over magnesium sulfate and concentrated to a clear oil (236 g, 100%). MS [M−H]− 183.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06576766B1 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-537875515702403782d288bfa9d63c7c |
| Source note | uspto-grants-2003_06 |