反应详情

Stir 1H-indol-7-ylamine with pyridine (1 equivalent) and methanesulfonyl chloride (1 equivalent) in dichloromethane for 12 hrs. Wash the reaction with 1N hydrochloric acid and water, dry over magnesium sulfate, and evaporate. Recrystallize the residue from isopropanol to obtain the title product as a purple solid (94%). MS (ES+), 210 (M), MS (ES−), 209 (M−1). LC/MS shows 95% purity.

1. washWash
2. customthe reaction with 1N hydrochloric acid and water
3. dry with materialdry over magnesium sulfate
4. customevaporate
5. customRecrystallize the residue from isopropanol