Aniline → HCID 13213174, compound

Participants

Reaction Steps

The procedure of Example 1 is repeated using 5.79 g (0.021 mmol) of 1-oxyl-4-benzoyloxy-2,2,6,6-tetramethylpiperidine, 5.05 g (49 mmol) of tert-butyl nitrite, 12.6 mg (0.125 mmol) of copper(II) fluoride, 120 mL of pyridine and 3.91 g (42 mmol) of aniline at 70° C. The crude product obtained is purified by vacuum flash chromatography (heptane) to give 4.10 g of the title compound as a yellowish oil in 55.3% yield. The structure is confirmed by mass spectrographic analysis. MS [M+1]354.

Provenance & Evidence