Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methylquinoline | HCID 10285 | — |
| Reactant | Ethyl 4-bromobutyrate | HCID 76300 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86759012 | HCID 86759012 | 77% |
Reaction Steps
A mixture of 1.43 g of lepidine and 2.5 g of ethyl 4-bromobutyrate is heated at 140-150° C. for 1.5 hours. The mixture is cooled to room temperature and stirred in 100 mL of ethyl acetate for 3 hours and filtered to yield 2.6 g of Compound 5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06579718B1 |
|---|
| Source dataset | uspto-grants-2003_06 |
|---|
| ORD ID | ord-48e255e1c8ad4316bf6796475436f341 |
|---|
| Source note | uspto-grants-2003_06 |
|---|
