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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1369561Generated: October 31, 2026

1-(Bromomethyl)-3-chloro-2-methylbenzene → 8-(3-Bromo-2-methylbenzylamino)-2,3-dimethylimidazo[1,2-a]pyridine

https://huagongshe.com/reaction/1369561

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-3-chloro-2-methylbenzeneHCID 10513091—
Reactant2,3-Dimethylimidazo[1,2-a]pyridin-8-amineHCID 21873980—
Reactant2-(Bromomethyl)-1-chloro-3-methylbenzeneHCID 22672606—
Product8-(3-Bromo-2-methylbenzylamino)-2,3-dimethylimidazo[1,2-a]pyridineHCID 22672595—

Reaction Steps

Example 1.34 and 1.35 are prepared from a mixture of 2-chloro-6-methylbenzylbromide and 3-chloro-2-methylbenzylbromide. The yields are referred to 8-amino-2,3-dimethylimidazo[1,2-a]pyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06579884B1
Source datasetuspto-grants-2003_06
ORD IDord-3c650399cf8a422cb09480bf970d9117
Source noteuspto-grants-2003_06