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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 136963Generated: October 25, 2026

Acetic Acid → Tert-butyl 3-[tert-butyl(dimethyl)silyl]oxy-2-[(3-chloro-4-cyano-2-methylanilino)methyl]pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/136963

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantEthyl AcetateHCID 8857—
Reactant3-(tert-Butyldimethylsilanyloxy)-2-formylpyrrolidine-1-carboxylic acid tert-butyl esterHCID 14735135—
Reactant4-Amino-2-chloro-3-methylbenzonitrileHCID 21875413—
ProductTert-butyl 3-[tert-butyl(dimethyl)silyl]oxy-2-[(3-chloro-4-cyano-2-methylanilino)methyl]pyrrolidine-1-carboxylateHCID 60066968—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-1f795eef5f0e4079bb94946133ff3ad9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)