HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → 4-Phenyl-3,4-dihydroquinolin-2(1h)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | 3-Phenylprop-2-enoyl chloride | HCID 66023 | — |
| Product | 4-Phenyl-3,4-dihydroquinolin-2(1h)-one | HCID 272509 | — |
Reaction Steps
4-Phenyl-3,4-dihydrocarbostyril (CAS #4888-33-9) was prepared in two steps using the procedure described by Conley, R. T.; Knopka, W. N. J. Org. Chem. 1964, 29, 496-497. The starting materials for this preparation were cinnamoyl chloride (Aldrich) and aniline (Aldrich). The title compound was purified by flash chromatography eluting with CH2Cl2/EtOAc (4:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06579867B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-689fdad653924864af583db8701b392c |
| Source note | uspto-grants-2003_06 |