HuagongsheHuagongshe Chemistry Print Report · For research reference only
DL-alanine → 2-Methylpropyl 2-aminopropanoate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | DL-alanine | HCID 602 | — |
| Reactant | Isobutanol | HCID 6560 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | 2-Methylpropyl 2-aminopropanoate hydrochloride | HCID 86200109 | — |
Reaction Steps
A mixture of 35.64 g (0.4 mol) of D,L-alanine (Aldrich), 44 mL (0.6 mol) of thionyl chloride (Aldrich) and 200 mL of iso-butanol was refluxed for 1.5 hours. The volatiles were removed at reduced pressure at 90° C. under reduced pressure to give the title compound as an oil, which was used without furtherpurification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06579867B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-4313609baac94f62a52a385f846428d4 |
| Source note | uspto-grants-2003_06 |