HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Naphthylamine → 2-[N-(naphth-2-yl)amino]butanoic Acid Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Naphthylamine | HCID 7057 | — |
| Reactant | Butanoic acid, 2-bromo-, ethyl ester | HCID 79039 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 2-[N-(naphth-2-yl)amino]butanoic Acid Ethyl Ester | HCID 10131322 | — |
Reaction Steps
Following General Procedure AJ above and using 2-aminonaphthalene (Aldrich) and ethyl 2-bromobutyrate (Aldrich), the title compound was prepared as a solid, m.p. 81-83° C. The reaction was monitored by silica gel tlc (Rf=0.5 in CHCl3). Purification was by chromatography (silica gel using chloroform as the eluant).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06579867B2 |
| Source dataset | uspto-grants-2003_06 |
| ORD ID | ord-d057df818fb44e2da9ffcbcec74919cd |
| Source note | uspto-grants-2003_06 |